Effects of intraoperative diltiazem infusion on flow changes in arterial and venous grafts in coronary artery bypass graft surgery

نویسندگان

  • Ozan Erdem
  • Mehmet Erdem Memetoğlu
  • Ali İhsan Tekin
  • Ümit Arslan
  • Özgür Akkaya
  • Rasim Kutlu
  • İlhan Gölbaşı
چکیده

OBJECTIVE This study aimed to show the effects of intra-operative diltiazem infusion on flow in arterial and venous grafts in coronary artery bypass graft surgery. METHODS Hundred fourty patients with a total of 361 grafts [205 (57%) arterial and 156 (43%) venous] underwent isolated coronary surgery. All the grafts were measured by intraoperative transit time flow meter intra-operatively. Group A (n=70) consisted of patients who received diltiazem infusion (dose of 2.5 microgram/kg/min), and Group B (n=70) didn't receive diltiazem infusion. RESULTS Mean graft flow values of left internal mammary artery were 53 ml/min in Group A and 40 ml/min in Group B (P<0.001). Pulsatility index (PI) values of left internal mammary artery for Group A and Group B were 2.6 and 3.0 respectively (P<0.001). No statistically significant difference was found between venous graft parameters. CONCLUSION We recommend an effect of diltiazem infusion in increasing graft flows in coronary artery bypass graft operations.

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عنوان ژورنال:

دوره 30  شماره 

صفحات  -

تاریخ انتشار 2015